Publications

A link to my Google Scholar is here.

All articles are also accessible on preprint servers, with links included below.

Preprints

  1. Murphy RJ, Gunasingh G, Haass NK, Simpson MJ. (2022). Formation and growth of co-culture tumour spheroids: new mathematical models and experiments. [preprint – bioRxiv]
  2. Spoerri L, Beaumont KA, Anfosso A, Murphy RJ, Browning AP, Gunasingh G, Haass NK. (2022). Real-time cell cycle imaging in a 3D cell culture model of melanoma, quantitative analysis, optical clearing, and mathematical modelling.

Published

  1. Murphy RJ, Gunasingh G, Haass NK, Simpson MJ. (2023). Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability. PLoS Computational Biology. doi:10.1371/journal.pcbi.1010833 [preprint – bioRxiv]
  2. Simpson MJ, Walker S, Studerus E, McCue SW, Murphy RJ, Maclaren OJ. (2023). Profile likelihood-based parameter and predictive interval analysis guides model choice for population dynamics. Mathematical Biosciences. doi:10.1016/j.mbs.2022.108950[preprint – bioRxiv]
  3. Murphy RJ, Maclaren OJ, Calabrese AR, Thomas PB, Warne DJ, Williams ED, Simpson MJ. (2022). Computationally efficient framework for diagnosing, understanding, and predicting biphasic population growth. Journal of the Royal Society Interface doi:10.1098/rsif.2022.0560 [preprint – bioRxiv]
  4. Murphy RJ, Browning AP, Gunasingh G, Haass NK, Simpson J. (2022). Designing and interpreting 4D tumour spheroid experiments. Communications Biology doi:10.1038/s42003-022-03018-3 [preprint – bioRxiv]
  5. Klowss J, Browning AP, Murphy RJ, Carr EJ, Plank MJ, Gunasingh G, Haass NK, Simpson MJ. (2022). A stochastic mathematical model of 4D tumour spheroids with real-time fluorescent cell cycle labelling. Journal of the Royal Society Interface doi:10.1098/rsif.2021.0903 [preprint – bioRxiv]
  6. Jolly MK, Murphy RJ, Bhatia S, Whitfield H, Redfern A, Davis MJ, Thompson EW. (2022). Measuring and modelling the epithelial mesenchymal hybrid state in cancer: clinical implications. Cells Tissues Organs. https://doi.org/10.1159/000515289 [preprint]
  7. Murphy RJ, Buenzli PR, Baker RE, Simpson MJ (2021). Travelling waves in a free boundary mechanobiological model of an epithelial tissue. Applied Mathematics Letters. https://doi.org/10.1016/j.aml.2020.106636
  8. Murphy RJ, Buenzli PR, Tambyah TA, Thompson EW, Hugo H, Baker RE, Simpson MJ. (2021). The role of mechanical interactions in EMT. Physical Biology. doi:10.1088/1478-3975/abf425 [preprint – bioRxiv]
  9. Browning AP, Sharp JA, Murphy RJ, Gunasingh G, Lawson B, Burrage K, Haass NK, Simpson MJ. (2021). Quantitative analysis of tumour spheroid structure. eLife doi:10.7554/eLife.73020 [preprint – bioRxiv]
  10. Reye G, Huang X, Haupt L, Murphy RJ, Northey JJ, Thompson EW, Momot K, Hugo H. (2021). Mechanical pressure driving proteoglycan expression in mammographic density: a self-perpetuating cycle? Journal of Mammary Gland Biology and Neoplasia. https://doi.org/10.1007/s10911-021-09494-3 [preprint]
  11. Murphy RJ, Buenzli PR, Baker RE, Simpson MJ (2020). Mechanical cell competition in heterogeneous epithelial tissues. Bulletin of Mathematical Biology. https://doi.org/10.1007/s11538-020-00807-x [preprint – bioRxiv]
  12. Tambyah T, Murphy RJ, Buenzli PR, Simpson MJ (2020). A free boundary mechanobiological model of epithelial tissues. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. https://doi.org/10.1098/rspa.2020.0528 [preprint – bioRxiv]
  13. Murphy RJ, Buenzli PR, Baker RE, Simpson MJ (2019). A one-dimensional individual-based mechanical model of cell movement in heterogeneous tissues and its coarse-grained approximation. Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences. https://doi.org/10.1098/rspa.2018.0838[preprint – bioRxiv]. This article was selected as cover image.

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